I always had issues booting off of an Ubuntu USB with persistent storage. The USBs kept getting so hot they died. At least I assume they died, within a couple of weeks I’d start encountering random errors nobody else ever seems to have had that nobody could help fix. But I have only tried Ubuntu and it works for long enough I’ve been able to do whatever I need to do
I always had issues booting off of an Ubuntu USB with persistent storage. The USBs kept getting so hot they died. At least I assume they died, within a couple of weeks I’d start encountering random errors nobody else ever seems to have had that nobody could help fix. But I have only tried Ubuntu and it works for long enough I’ve been able to do whatever I need to do