Two people have died and a woman is in a critical condition after a three-vehicle crash in the Legacy Way tunnel in Brisbane’s inner-west on Wednesday afternoon.

Queensland Police said preliminary investigations indicated a black Audi S3 was travelling north in the tunnel when it crashed into a silver sedan, which subsequently crashed into a small truck.

The driver and sole occupant of the Audi, a man in his 50s, died at the scene.

A woman in 20s, who was a passenger in the silver sedan, also died at the scene.

Police said the driver of the sedan was taken to the Royal Brisbane and Women’s Hospital in a critical condition.

The driver of the truck was taken to hospital with non-life-threatening injuries.