A recent survey reveals the foods that people are less likely to eat once they start taking GLP-1 medications like Ozempic.
  • dumblederp
    2·
    14 days ago

    the glp-1 antagonists mimic low grade ketosis

    Do you have a reference for that?

    • jet@hackertalks.comEnglish
      1·
      14 days ago

      https://doi.org/10.1038/s41366-025-01749-x

      TLDR: GLP-1 and SGLT-2 drugs have been associated with EKA in the literature; Treating physicians need to be aware of ketone levels of their patients, or at least keep the EKA as a possible differential diagnosis. This hints at a underlying mechanism of benefit between ketogenic metabolism and these drugs.

      https://doi.org/10.1016/j.clinthera.2016.11.002

      SGLT2 inhibitors have been associated with increases in ketone-associated adverse events.

      these data suggest a causal relationship between SGLT2 inhibitors and an asymptomatic rise in ketone bodies