A very informative conversation between a researcher and a practicing clinician.
Dr. Matthew Phillips is a clinical and research neurologist and the director of neurology at Waikato Hospital, Hamilton, New Zealand. His foremost passion is to explore the potential feasibility, safety, and efficacy of metabolic strategies, particularly fasting and ketogenic diets, in creating alternate metabolic states that may benefit people with a variety of neurological disorders. His team conducted the world’s first randomized trials involving a ketogenic diet in people with both Parkinson’s and Alzheimer’s disease, as well as the first published application of a fasting and ketogenic diet protocol in people with amyotrophic lateral sclerosis and Huntington’s disease. He is currently conducting a clinical trial in glioblastoma, which combines standard treatments with the most intensive fasting and ketogenic diet protocol ever applied to a group of patients with advanced cancer.
the paper they talk about https://pubmed.ncbi.nlm.nih.gov/35656107/
Yeah this guy is the business. His Alzheimer’s experiment was two groups 12 weeks on dietician designed low fat for one group and 12 weeks on keto for the other group
Then both groups go on normal diet for 12 weeks to clear any effects from the previous part
Then they swap. The first group does keto for 12 weeks and the second follows the dietician’s low fat diet
So each person had both treatments
Note that there is no current treatment so you couldn’t really compare to the current standard of care