Here is a good summary article discussing this topic that I found if people want more reading.

I am fortunate enough to not react to poison ivy and have removed loads of it by hand through pulling it out (I still wear gloves though). I don’t really want to use chemicals because it tends to grow mixed in with some other landscaped areas and I don’t want to kill other things through collateral damage. I haven’t eradicated it this way, but each year less and less of it comes back, so it is a war of attrition.