This is exactly what happens. Actually the whole Wayland/xorg thing is not necessary, simply exiting a Wayland session and starting a new one will probably have the same effect, might depend on compositor. But it doesn’t help knowing that it’s the cause, I’ve known it for years, no closer to a solution. Obviously closing the tmux session and starting over is a “fix” in the same way that turning the machine off and on again is a fix. Kinda defeats the purpose of persistent tmux sessions.
I’m between The Black Parade (the album) by My Chemical Romance, an alt rock opera masterpiece imo, and Hamilton, the Broadway cast recording. I feel like the former might not work as well when removed from its time, but I bet it still would blow my mind.