I often see the sentiment that YouTube and adblockers will be forever locked in a cat-and-mouse game. However, for many years now, Twitch has entirely eliminated adblocking on desktop web.
What is stopping YouTube from replicating Twitch’s advertising strategy of embedding ads directly into their videos?
There will just be another popup and everything is fine. Ads are youtube business model, they can ask you to deactivate adblock, pay up or leave the site like a lot of news sites do. Running anti-adblockers is entirely within the law if you get informed about it on the site.